DocBook V4.x is feature frozen
DocBook V5.0 offers new functionality
annotations
more flexible linking system
unified info
markup
DocBook V5.0 is more extensible
thanks to namespaces it can be easily mixed with other vocabularies like SVG, MathML, XHTML or even FooBarML
DocBook V5.0 is easier to customize
RELAX NG based customizations are much more easier and faster to create then DTD based